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Folic acid 400 mcg/day from 1 month pre-conception through first 12 weeks reduces NTD risk by ~70%. 1 mg for diabetes/obesity; 4–5 mg for high-risk.

Evidence-based guide to methotrexate folic acid dosing in rheumatoid arthritis: 1 mg vs 5 mg protocols, folinic acid rescue, hepatotoxicity prevention, and toxicity monitoring.

Which epilepsy medication is safe in pregnancy? Evidence-based guide ranking anticonvulsants by teratogenic risk, with dosing, folic acid advice, and monitoring.