This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.
Description, Dosage, Side Effects, Contraindications. Data from EMA, URPL, openFDA and other regulatory sources.
| Levothyroxine | Liothyronine | |
|---|---|---|
| Active Substances | LEVOTHYROXINE | Liothyronine I 125 |
| Form | LIQUID | — |
| Dosage | 12 [hp_X]/mL | — |
| Route | ORAL | — |
| Manufacturer | Energique, Inc. | — |
| Indications | This medication is a thyroid hormone, prescribed for hypothyroidism. It works by replacing thyroid hormone when the body does not make enough on its own. | This medication is a thyroid hormone, prescribed for myxedema. It is also used to treat goiter (enlarged thyroid gland). It reverses hypothyroidism symptoms. |
| Side Effects | General - Fatigue, increased appetite, weight loss, heat intolerance, fever and excessive sweating. Central nervous system - Headache, hyperactivity, nervousness, anxiety, irritability, emotional lability and sleeplessness. Musculoskeletal - Tremor and muscle weakness. Heart - Palpitations, fast heart rate, abnormal heart rhythm, increased pulse and blood pressure, heart failure, chest pain and heart attack. Respiratory - Difficulty in breathing. Gastrointestinal - Diarrhea, vomiting, abdominal cramps and elevation in liver function tests. Skin - Hair loss and flushing. Endocrine - Decreased bone mineral density. Reproductive - Menstrual irregularities and impaired fertility. |
Levothyroxine (INN: LEVOTHYROXINE) and Liothyronine (INN: Liothyronine I 125) differ in active substance, indications, and safety profile. The table above summarizes the clinical differences from regulatory documents.
Combination safety depends on mechanisms and your health profile. Use our interactions checker and always consult your doctor or pharmacist before combining medications.
Both drugs are approved when used per label. Safety is patient-specific — the better choice depends on your condition, other medications, allergies, and comorbidities. Consult a healthcare professional for personalized advice.
This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.
| Central Nervous System - Tremor, headache, nervousness, irritability and sleeplessness. Gastrointestinal - Weight loss, stomach upset, vomiting, diarrhea, stomach cramps and increased appetite. Miscellaneous - Excessive sweating, fever, changes in menstrual cycle and sensitivity to heat. |
| Warnings | • Caution should be exercised in patients with history of trouble in swallowing, heart problems, high blood pressure, bleeding disorder, anemia, sugar, jaundice, underactive adrenal or pituitary gland, osteoporosis, infertility, adrenal gland problems, thyroid problems, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding. • Monitor blood sugar level regularly while taking this medication. • Dietary fiber may decrease the absorption of this medication; consult with your doctor for proper diet. | • Caution should be exercised in patients with history of heart or blood vessel disease, high blood pressure, overactive thyroid, any allergy, who are taking other medications, during pregnancy and breastfeeding. • It may affect blood sugar level, monitor sugar level regularly. • Patient may experience with certain symptoms like shaking of the hands, nervousness, difficulty in sleeping, headache, change in appetite, diarrhea, weight loss etc., if it is so consult with your doctor. |
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