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USDailyMed:Labetalol AU:C C07AG01(WHO) AU:S4(Prescription only)In general: ℞ (Prescription only) (RS)-2-Hydroxy-5-[1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl]benzamide 36894-69-6Y 3869 7207 DB00598Y 3734Y R5H8897N95 D08106Yas HCl:D00600Y CHEBI:6343Y ChEMBL429Y DTXSID2023191 Interactive image c1ccccc1CCC(C)NCC(O)c2ccc(O)c(C(=O)N)c2 InChI=1S/C19H24N2O3/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24)YKey:SGUAF‍‍‍‍‍‍​​​‍​​​​​​YQXFOLMHL-UHFFFAOYSA-NY Labetalolis a medication used to treathigh blood pressureand in long term management ofangina.This includesessential hypertension,hypertensive emergencies, andhypertension of pregnancy.In essential hypertension it is generally less preferred than a number of otherblood pressure medications.It can be givenby mouthor byinjection into a vein. Common side effects includelow blood pressure with standing, dizziness, feeling tired, and nausea.Serious side effects may includelow blood pressure,liver problems,heart failure, andbronchospasm.Use appears safe in the latter part ofpregnancyand it is not expected to cause problems duringbreastfeeding.It works by blocking the activation ofβ-andα-adrenergic receptors. Labetalol was patented in 1966 and came into medical use in 1977.It is available as ageneric medication.In 2023, it was the 232nd most commonly prescribed medication in the United States, with more than 1million prescriptions.