What is Flucytosine used for?

Flucytosine belongs to the group of medicines known as antifungals. It is used to treat certain types of fungal infections. For the treatment (in combination with amphotericin B) of serious infections caused by susceptible strains of Candida (septicaemia, endocarditis, and urinary tract infections) and/or Cryptococcus (meningitis and pulmonary infections). Hypersensitivity to Flucytosine.

How does Flucytosine work?

Although the exact mechanism of action is unknown, it has been proposed that Flucytosine acts directly on fungal organisms by competitive inhibition of purine and pyrimidine uptake, and indirectly through intracellular metabolism to 5-fluorouracil.

What pharmaceutical form is Flucytosine available in?

Flucytosine: Roztwór do infuzji 10 mg/ml (dożylna)

Is Flucytosine OTC or prescription only?

Flucytosine requires a doctor's prescription.

What are the side effects of Flucytosine?

If you experience any of the following serious side effects, stop taking Flucytosine and seek emergency medical attention or contact your doctor immediately: – an allergic reaction (difficulty breathing, throat tightness, swelling of the lips, tongue, face, or urticaria); – chest pain; – yellowing of the skin or eyes; – little or no urine output; – confusion or hallucinations; – numbness or tingling; or – hearing loss. Other less serious side effects may be more likely to occur

Who manufactures Flucytosine?

Bausch Health Ireland Ltd. (Polska)

What ATC class does Flucytosine belong to?

Flucytosine: ATC J02AX01. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

Flucytosine

This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.

Flucytosine — Description, Dosage, Side Effects | PillsCard

⚠️ Warnings

Pregnancy Pregnancy: This medicine should not be used in pregnant women or in women likely to become pregnant, unless the benefit outweighs the risk. Breastfeeding Breastfeeding: A decision should be made whether to discontinue breastfeeding or discontinue the medicine, taking into account the importance of the medicine to the mother. Your doctor should check your progress at regular visits to make sure that Flucytosine is not causing unwanted effects. Flucytosine may cause blood problems.‍‍‍‍‍‍‍ These problems may result in an increased risk of infection, slow healing, and bleeding of the gums. Therefore, you should take care when using regular toothbrushes, dental floss, and toothpicks. Whenever possible, dental treatment should be completed before starting Flucytosine or delayed until blood counts return to normal. Speak to your doctor or dentist if you have any questions about proper oral hygiene (mouth care) during treatment. Flucytosine may make your skin more sensitive to sunlight than usual. Exposure to sunlight, even for brief periods, may cause skin irritation, itching, redness or other skin discolouration, or severe sunburn. When you start taking Flucytosine: – Stay out of direct sunlight, especially between 10:00 and 15:00, if possible. – Wear protective clothing, including a hat. Also, wear sunglasses. – Apply a sunscreen product with a sun protection factor (SPF) of at least 15. Some patients may need a product with a higher SPF number, especially if they have fair skin. If you have any questions about this, check with your healthcare professional. – Apply a lip balm with at least SPF 15 protection. – Do not use sunlamps or tanning beds. If you have a severe reaction to sunlight, speak to your doctor. Flucytosine may also cause some people to become dizzy, light-headed, drowsy, or less alert than normal. Make sure you know how you react to the effects of Flucytosine before driving, using machines, or performing tasks that could be dangerous if you are dizzy or less alert. If these reactions are particularly troublesome, speak to your doctor.

Flucytosine

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