This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.
ANDEMBRY — Description, Dosage, Side Effects | PillsCard
OTC
ANDEMBRY
200 mg, Roztwór do wstrzykiwań we wstrzykiwaczu
INN: Garadacimabum
Available in:
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Form
Roztwór do wstrzykiwań we wstrzykiwaczu
Dosage
200 mg
Route
—
Storage
Storage and Handling Do not freeze. Do not shake. Keep the prefilled autoinjector and prefilled syringe with needle safety device in the original carton to protect from light. Store the prefilled autoinjector and prefilled syringe with needle safety device refrigerated at 36°F to 46°F (2°C - 8°C).
User Reviews
Reviews reflect personal experiences and are not medical advice. Always consult your doctor.
About This Product
Manufacturer
CSL Behring GmbH
ATC Code
B06AC
Source
URPL
11 DESCRIPTION Garadacimab-gxii, an activated Factor XII (FXIIa) inhibitor, is a recombinant, fully human, monoclonal antibody (IgG4/ λ -light chain) produced in Chinese Hamster Ovary (CHO) cells. Based on the amino acid sequence, the molecular weight of garadacimab-gxii is approximately 148 kDa. ANDEMBRY (garadacimab-gxii) injection is a sterile, preservative-free, slightly opalescent to clear, brownish-yellow to yellow solution for subcutaneous use. Each 1.2 mL prefilled autoinjector or prefilled syringe with needle safety device of ANDEMBRY contains 200 mg of garadacimab-gxii, arginine monohydrochloride (37.9 mg), histidine (3.7 mg), polysorbate 80 (0.24 mg), proline (19.3 mg), and water for injection, USP. The pH is 6.1.
⚠️ Warnings
Before use, ANDEMBRY should be visually inspected for appearance by gentle inversion. The solution should be slightly opalescent to clear, brownish-yellow to yellow. Solutions that are discolured or contain particles should not be used.
Do not shake.
Administration steps
After removing the pre-filled pen from the refrigerator, wait 30 minutes before injecting to allow the solution to reach room temperature. Inject ANDEMBRY subcutaneously into the abdomen, thigh or upper arm (see section 4.2).
Injection with the pre-filled pen may take up to 15 seconds.
Listen for the first 'click' (this signals the start of injection, and the yellow plunger will start to move across the window). Keep pressing and watch the yellow plunger move down to fill the window. A second 'click' will be heard and the viewing window will be completely yellow. Wait an extra 5 seconds to make sure the full dose was received.
Each pre-filled pen is for single use only. Discard the pre-filled pen after injection is completed in a sharps container or closed puncture resistant container.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
The instructions for use are provided within the Patient Information Leaflet.