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( ARTG ) Rheumatoid Arthritis,ABRILADA is indicated for reducing signs and symptoms, as well as inhibiting the progression of structural damage in adult patients with moderate to severely active rheumatoid arthritis.‍‍‍‍‍‍​​​‍​​​​​​ This includes the treatment of patients with recently diagnosed moderate to severely active disease who have not received methotrexate. ABRILADA can be used alone or in combination with methotrexate.Juvenile Idiopathic Arthritis,1) Polyarticular Juvenile Idiopathic Arthritis - ABRILADA in combination with methotrexate is indicated for reducing the signs and symptoms of moderately to severely active polyarticular juvenile idiopathic arthritis in patients 2 years of age and older who have had an inadequate response to one or more disease modifying antirheumatic drugs (DMARDs). ABRILADA can be given as monotherapy in case of intolerance to methotrexate or when continued treatment with methotrexate is inappropriate.,2) Enthesitis-Related Arthritis - ABRILADA is indicated for the treatment of enthesitis-related arthritis in children, who have had an inadequate response to, or who are intolerant to, conventional therapy.Psoriatic Arthritis,ABRILADA is indicated for the treatment of signs and symptoms, as well as inhibiting the progression of structural damage, of moderate to severely active psoriatic arthritis in adult patients where response to previous DMARDs has been inadequate.Ankylosing Spondylitis,ABRILADA is indicated for reducing signs and symptoms in patients with active ankylosing spondylitis.Crohns Disease in Adults and Children (6 years and above),ABRILADA is indicated for the treatment of moderate to severe Crohns disease, to reduce the signs and symptoms of the disease and to induce and maintain clinical remission in patients;, who have had an inadequate response to conventional therapies or,, who have lost response to or are intolerant to infliximab.Ulcerative colitis,ABRILADA is indicated for the treatment of moderate to severe ulcerative colitis in adult patients who have had an inadequate response to conventional therapy or who are intolerant to or have medical contraindications for such therapies. Patients should show a clinical response within 8 weeks of treatment to continue treatment beyond that time. (see 5.1 PHARMACODYNAMIC PROPERTIES - CLINICAL TRIALS).Psoriasis in Adults and Children,ABRILADA is indicated for the treatment of moderate to severe chronic plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy. ABRILADA is indicated for the treatment of severe chronic plaque psoriasis in children and adolescent patients from 4 years of age who have had an inadequate response to or are inappropriate candidates for topical therapy and phototherapy.Hidradenitis Suppurativa in Adults and Adolescents (from 12 years of age),ABRILADA is indicated for the treatment of active moderate to severe hidradenitis suppurativa (acne inversa) in patients with an inadequate response to conventional systemic hidradenitis suppurativa therapy.Uveitis,ABRILADA is indicated for the treatment of non-infectious intermediate, posterior and panuveitis in adult patients who have had an inadequate response to corticosteroids, in patients in need of corticosteroid sparing, or in whom corticosteroid treatment is inappropriate.