HYDROCHLOROTHIAZIDE; QUINAPRIL (QUINAPRIL HYDROCHLORIDE)

USDailyMed:Quinapril C09AA06(WHO) US:℞-onlyIn general: ℞ (Prescription only) (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid 85441-61-8Y 54892 6350 DB00881Y 49565Y RJ84Y44811 D03752Y CHEBI:8713Y ChEMBL1592Y DTXSID4023547 Interactive image O=C(OCC)[C@@H](N[C@H](C(=O)N2[C@H](C(=O)O)Cc1c(cccc1)C2)C)CCc3ccccc3 InChI=1S/C25H30N2O5/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(‍‍‍‍‍‍​​​‍​​​​​​20)15-22(27)24(29)30/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30)/t17-,21-,22-/m0/s1YKey:JSDRRTOADPPCHY-HSQYWUDLSA-NY Quinapril, sold under the brand nameAccuprilby thePfizercorporation, is amedicationused to treathigh blood pressure(hypertension),heart failure, anddiabetic kidney disease.It is a first line treatment for high blood pressure.It is takenby mouth. Common side effects include headaches, dizziness, feeling tired, and cough.Serious side effects may include liver problems,low blood pressure,angioedema,kidney problems, andhigh blood potassium.Use inpregnancyandbreastfeedingis not recommended.It is among a class of drugs calledACE inhibitorsand works by decreasingrenin-angiotensin-aldosterone systemactivity. Quinapril was patented in 1980 and came into medical use in 1989.It is available as ageneric medication.In 2020, it was the 253rd most commonly prescribed medication in the United States, with more than 1million prescriptions.