Question 1

What is PEMETREXED (PEMETREXED DISODIUM) used for?

Accepted Answer

In February 2004, the U.S.Food and Drug Administration(FDA) approved pemetrexed for treatment of malignant pleural mesothelioma, a type of tumor of themesothelium, the thin layer of tissue that﻿‍‍‍‍‍‍​​​‍​​​​​​﻿ covers many of the internal organs, in combination withcisplatinfor patients whose disease is either unresectable or who are not otherwise candidates for curative surgery.In September 2008, the FDA granted approval as a first-line treatment, in combination with cisplatin, against locally

Question 2

How does PEMETREXED (PEMETREXED DISODIUM) work?

Accepted Answer

USDailyMed:Pemetrexed
AU:D
L01BA04(WHO)
AU:S4(Prescription only)UK:POM(Prescription only)US:℞-onlyEU:Rx-only
(2S)-2-{[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino}pentanedioic acid
137281-23-3N
135410875
DB00642Y
393879Y
04Q9AIZ7NO
D07472Yas ﻿‍‍‍‍‍‍​​​‍​​​​​​﻿salt:D06503Y
ChEMBL225072Y
DTXSID2048329
Interactive image
Nc3nc2[nH]cc(CCc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=

Question 3

What is the active ingredient in PEMETREXED (PEMETREXED DISODIUM)?

Accepted Answer

PEMETREXED (PEMETREXED DISODIUM)

Question 4

Does PEMETREXED (PEMETREXED DISODIUM) interact with other medications?

Accepted Answer

The administration of cisplatin andvitamin B12concomitantly does not modify thepharmacokineticsof the pemetrexed.
It was recently shown that pemetrexed may play a role in cisplatin resistance in lung cancer by increa﻿‍‍‍‍‍‍​​​‍​​​​​​﻿sing the expression of Orai3 calcium channels as well as the expression of certain ABC transporters like MDR1 and MRP-5 responsible for cisplatin efflux and therefore a reduction of the effect of cisplatinAs current therapies are based on the co-administration of pe

Question 5

Who manufactures PEMETREXED (PEMETREXED DISODIUM)?

Accepted Answer

JAMP PHARMA CORPORATION

Question 6

What ATC class does PEMETREXED (PEMETREXED DISODIUM) belong to?

Accepted Answer

PEMETREXED (PEMETREXED DISODIUM): ATC L01BA04. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

PEMETREXED (PEMETREXED DISODIUM)

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