Carboplatin - Indications, Dosage, Side Effects and Precautions

L01XA02(WHO) ] AU:S4(Prescription only)CA:℞-onlyIn general: ℞ (Prescription only) cis-diammine(cyclobutane-1,1-dicarboxylate-O,O')platinum(II) 41575-94-4Y 498142 DB00958Y 8514637Y BG3F62OND5 D01363Y CHEBI:31355Y ChEMBL288376N DTXSID3046742 Interactive image C1CC2(C1)C(=O)O[Pt-2]([NH3+])([NH3+])OC2=O InChI=1S/C6H8O4.2H3N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H3;/q;;;+2/p-2YKey:OLESAACUTLOWQZ-UHFFFAOYSA-LY Carboplatin, sol‍‍‍‍‍‍​​​‍​​​​​​d under the brand nameParaplatinamong others, is achemotherapymedication used to treat a number of forms ofcancer.This includesovarian cancer,lung cancer,head and neck cancer,brain cancer, andneuroblastoma.It is administered byinjection into a veinsometimes via aport. Side effects generally occur.Common side effects includelow blood cell levels, nausea, andelectrolyte problems.Other serious side effects includeallergic reactionsandmutagenesis. It may becarcinogenic, but further research is needed to confirm this.Use duringpregnancymay result in harm to the baby.Carboplatin is in theplatinum-based antineoplasticfamily of medications and works by interfering with duplication ofDNA. Carboplatin was developed as a less toxic analogue ofcisplatin.It was patented in 1972 and approved for medical use in 1989.It is on the 2023World Health Organization's List of Essential Medicines.