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Lisdexamfetamine — Description, Dosage, Side Effects | PillsCard
OTC
Lisdexamfetamine
INN: LISDEXAMFETAMINE DIMESYLATE
Data updated: 2026-05-02
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About This Product
Manufacturer
User Reviews
Reviews reflect personal experiences and are not medical advice. Always consult your doctor.
TEVA CANADA LIMITED
ATC Code
N06BA12
Source
DPD · 02535580
USDailyMed:Lisdexamfetamine
AU:B3
N06BA12(WHO)
AU:S8(Controlled drug)BR:Class A3(Psychoactive drugs)CA: Controlled Drug (CDSA I)DE:Anlage III(Special prescription form required)NZ:Class BUK:Class BUS:Schedule IIEU:Rx-onlySE: Förteckning II
(2S)-2,6-Diamino-N-[(1S)-1-methyl-2-phenylethyl]hexanamide
608137-32-2Y[IUPHAR]
11597698
7213
DB01255Y
9772458Y
H645GUL8KJ
D08130as salt:D04747
ChEMBL1201222Y
DTXSID00209652
Interactive image
O=C(N[C@H](Cc1ccccc1)C)[C@@H](N)CCCCN
InChI=1S/C15H25N3O/c1-12(11-13-7-3-2-4-8-13)18-15(19)14(17)9-5-6-10-16/h2-4,7-8,12,14H,5-6,9-11,16-17H2,1H3,(H,18,19)/t12-,14-/m0/s1YKey:VOBHXZCDAVEXEY-JSGCOSHPSA-NY
Lisdexamfetamine, sold under the brand namesVyvanse(/ˈvaɪ.væns/,VY-vans) andElvanseamong others, is astimulantmedication that is used as a treatment forattention deficit hyperactivity disorder(ADHD) in both children and adults, and for moderate-to-severebinge eating disorderin adults.Aprodrugofdextroamphetamine, lisdexamfetamine is takenby mouth. Its effects generally begin within 90 minutes and last for up to 14 hours.
Common side effects of lisdexamfetamine includeloss of appetite,anxiety,diarrhea,trouble sleeping,irritability, andnausea.Rare but serious side effects includemania,sudden cardiac deathin those withunderlying heart problems, andpsychosis.It has a high potential forsubstance abuse.Serotonin syndromemay occur if used with certain other medications.Its use duringpregnancymay result in harm to thefetus, and use duringbreastfeedingis not recommended by the manufactureras dextroamphetamine (its metabolite) can pass through the breastmilk.
Lisdexamfetamine is an inactive prodrug that is formed by thecondensationofL-lysine, a naturally occurringamino acid, and dextroamphetamine.In the body, metabolic action reverses this process to release the active agent, thecentral nervous system(CNS)stimulantdextroamphetamine.
Lisdexamfetamine was approved for medical use in the United States in 2007 and in the European Union in 2012.In 2023, it was the 76th most commonly prescribed medication in the United States, with more than 9million prescriptions.It is aClass B controlled substancein the United Kingdom, aSchedule 8 controlled drugin Australia, and aSchedule II controlled substancein the United States.
⚠️ Warnings
•Caution should also be exercised in patients with history of irregular heartbeat or heart attack, high blood pressure, thickening of the arteries, or other heart problems, depression, bipolar disorder, abnormally excited mood, uncontrollable movements, repetition of sounds or words that is hard to control, suicidal thoughts.