FUROSEMIDE

USDailyMed:Furosemide AU:C C03CA01(WHO) AU:S4(Prescription only)UK:POM(Prescription only)US:℞-onlyIn general: ℞ (Prescription only) 4-Chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid 54-31-9Y 3440 DB00695Y 3322Y 7LXU5N7ZO5 D00331Y CHEBI:47426Y ChEMBL35Y DTXSID6020648 Interactive image o1cccc1CNc(cc2Cl)c(C(=O)O)cc2S(=O)(=O)N InChI=1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)YKey:ZZUFCTLCJUWOSV-UHFFFAOYSA-NY Furosemide, sold under the brand nameLasixamong others, is aloop diureticmedication used to treatedemadue toheart failure,liver scarring, orkidney disease.Furosemide may also be used for the treatment ofhigh blood pressure.It can be takenintravenouslyororally.Whe​​​‍​​‍​​​​‍​​‍‍n given intravenously, furosemide typically takes effect within five minutes; when taken orally, it typically metabolizes within an hour. Common side effects includeorthostatic hypotension(decrease inblood pressurewhile standing, and associatedlightheadedness),tinnitus(ringing in the ears), andphotosensitivity(sensitivity to light).Potentially serious side effects includeelectrolyte abnormalities,low blood pressure, andhearing loss.It is recommended thatserumelectrolytes(especiallypotassium), serumCO2,creatinine,BUNlevels, andliverandkidneyfunctioning be monitored in patients taking furosemide. It is also recommended to be alert for the occurrence of any potentialblood dyscrasias. Furosemide works by decreasing the reabsorption of sodium by the kidneys.Common side effects of furosemide injection include hypokalemia (low potassium level), hypotension (low blood pressure), and dizziness. Furosemide was patented in 1959 and approved for medical use in 1964.It is on theWorld Health Organization's List of Essential Medicines.In the United States, it is available as ageneric medication.In 2023, it was the 29th most commonly prescribed medication in the United States, with more than 19million prescriptions.In 2020/21 it was the twentieth most prescribed medication in England.It is on theWorld Anti-Doping Agency's banned drug list due to concerns that it may mask other drugs.It has also been used in race horses for the treatment and prevention ofexercise-induced pulmonary hemorrhage.