This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.
OTC
Apremilast
INN: APREMILAST
Data updated: 2026-05-14
Available in:
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About This Product
Manufacturer
User Reviews
Reviews reflect personal experiences and are not medical advice. Always consult your doctor.
APOTEX INC
ATC Code
L04AA32
Source
DPD · 02538172
USDailyMed:Apremilast
AU:B3
L04AA32(WHO)
AU:S4(Prescription only)UK:POM(Prescription only)US:℞-onlyEU:Rx-onlyIn general: ℞ (Prescription only)
N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide
608141-41-9
11561674
DB05676
9736448
UP7QBP99PN
D08860
CHEBI:78540
ChEMBL514800
DTXSID30976289
Interactive image
O=S(=O)(C)C[C@H](c1ccc(OC)c(OCC)c1)N3C(=O)c2cccc(c2C3=O)NC(=O)C
InChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1Key:IMOZEMNVLZVGJZ-QGZVFWFLSA-N
Apremilast, sold under the brand nameOtezlaamong others, is a medication for the treatment of certain types ofpsoriasisandpsoriatic arthritis.The drug acts as a selective inhibitor of the enzymephosphodiesterase 4(PDE4).It is takenby mouth.
⚠️ Warnings
•Patients are advised to be alert for the emergence of symptoms of depression, suicidal thoughts or any other mood changes and if such changes occur to contact with their doctor
•Carefully weigh the risks and benefits of apremilast in patients with a history of depression and/or suicidal thoughts.
•Weight should be monitored regularly as apremilast can decrease weight. If significant weight loss occurs, evaluate weight loss and consider discontinuation of apremilast