This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.
MAYZENT — Description, Dosage, Side Effects | PillsCard
OTC
MAYZENT
INN: SIPONIMOD
Data updated: 2026-05-14
Available in:
🇨🇿🇩🇪🇬🇧🇵🇹🇸🇰
Form
—
Dosage
—
Route
—
Storage
—
About This Product
Manufacturer
User Reviews
Reviews reflect personal experiences and are not medical advice. Always consult your doctor.
NOVARTIS PHARMACEUTICALS CANADA INC
ATC Code
L04AE03
Source
DPD · 02543370
USDailyMed:Siponimod
AU:D
L04AE03(WHO)
AU:S4(Prescription only)CA:℞-onlyUK:POM(Prescription only)US:℞-onlyEU:Rx-onlyIn general: ℞ (Prescription only)
1-({4-[(1E)-1-({[4-cyclohexyl- 3-(trifluoromethyl)phenyl]methoxy}imino)ethyl]-2-ethylphenyl}methyl)azetidine-3-carboxylic acid
1230487-00-9
44599207
DB12371
29315058
RR6P8L282I
D11460as salt:D11072
ChEMBL2336071
DTXSID40153847
Interactive image
CCc1cc(C(C)=NOCc2ccc(C3CCCCC3)c(C(F)(F)F)c2)ccc1CN1CC(C(=O)O)C1
InChI=1S/C29H35F3N2O3/c1-3-21-14-23(10-11-24(21)15-34-16-25(17-34)28(35)36)19(2)33-37-18-20-9-12-26(22-7-5-4-6-8-22)27(13-20)29(30,31)32/h9-14,22,25H,3-8,15-18H2,1-2H3,(H,35,36)/b33-19+Key:KIHYPELVXPAIDH-HNSNBQBZSA-N
Siponimod, sold under the brand nameMayzent, is a selectivesphingosine-1-phosphatereceptormodulator for oral use that is used formultiple sclerosis(MS).It is intended for once-daily oral administration.
In March 2019, it was approved in the United States to treat adults with relapsing forms of multiple sclerosis, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease.
⚠️ Warnings
1. Siponimod may increase the chance of infections. So, obtain a complete blood count (CBC) before initiating treatment.
2. Eye evaluation is recommended before starting treatment as there is an increased chance of macular swelling
3. Siponimod may lower heart rate. So, get cardiologist consultation before concomitant use with other drugs that decrease heart rate.
4. Siponimod may cause a decline in lung function. So, assess pulmonary function before starting the drug.
5. Check liver enzymes before initiation of drug.
6. Monitor BP frequently during treatment.
7. Women of childbearing potential should use effective contraception during and for 10 days after stopping Siponimod.