What is Pamidronate used for?

This medication is a bisphosphonate, prescribed for Paget's disease (a condition in which the bones are soft and weak and may be deformed, painful, or easily broken), high blood calcium levels (hypercalcemia) that may occur with cancer or multiple myeloma especially when the bone is affected. It works by slowing bone breakdown, increasing bone density (thickness) and decreasing the amount of calcium released from the bones into the blood.

What are the side effects of Pamidronate?

General - Generalized pain, fever, reactivation of viral diseases. Flu-like reaction may occur initially. Heart - High blood pressure, abnormal heart rate or rhythm, heart failure, syncope. Central Nervous System - Confusion, visual hallucinations, electrolyte imbalance, sleeplessness, nervousness, drowsiness, mental or mood changes. Gastrointestinal - Abdominal pain, loss of appetite, constipation, nausea, vomiting, diarrhea, mouth ulcer, gastrointestinal hemorrha

What precautions should be taken with Pamidronate?

•Do not take calcium and vitamin D supplement if you have high blood calcium levels. If possible, avoid dental treatment while you are using this medication to prevent osteonecrosis of the jaw. • It may increase the risk of heart failure in patients with heart disease. Inject slowly to reduce risk of adverse effects (e.g. injection site reactions, kidney impairment). ♦ Monitor blood counts in patients with preexisting poor blood counts .

What ATC class does Pamidronate belong to?

Pamidronate: ATC M05BA03. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

OTC

Pamidronate

INN: PAMIDRONATE DISODIUM

Data updated: 2026-05-02

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