CEPACOL INSTASOOTHE SORE THROAT RELIEF + SOOTHING COMFORT

R02AA12(WHO) 4-hexylbenzene-1,3-diol 136-77-6Y 3610 21106121Y R9QTB5E82N D04441Y ChEMBL443605Y DTXSID1020699 Interactive image Oc1cc(O)ccc1CCCCCC InChI=1S/C12H18O2/c1-2-3-4-5-6-10-7-8-11(13)9-12(10)14/h7-9,13-14H,2-6H2,1H3YKey:WFJIVOKAWHGMBH-UHFFFAOYSA-NY 4-Hexylresorcinolis anorganic compoundwithlocal anaesthetic,antiseptic, andanthelminticproperties. As anantiseptic, it is marketed asS.T.37by Numark Laboratories, Inc. (in a 0.1% solution) for oral pain relief and as a topical antiseptic. It is available for use topically on smallskin infectionsor as an ingredient inthroat lozenges. As ananthelmintic, 4-hexylresorcinol was sold under the brand Crystoids.Sytheon Ltd., USA markets 4-hexylresorcinol (trade named Synovea HR). Johnson & Johnsonuses 4-hexylresorcinol in itsNeutrogena,Aveeno, and RoC skincare products as ananti-aging cream. 4-Hexylresorcinol has been used commercially by many cosmetic and personal care companies, such asMary Kay,Clarins,Unilever,Murad,Facetheory,Arbonne, and many small and large companies. A study published inChemical Research in Toxicologyshows that 4-hexylresorcinol used as afood additive(E-586) exhibits some estrogenic activity, i.e. resembles action of the female sex hormoneestrogen. However, a recent study published inApplied Sciencesshows that 4-hexylresorcinol did not change the expression of estrogen receptor-α, -β, or p-ERK1/2 in MCF-7 cells. In an ovariectomized animal model, the 4HR group showed similar levels of ERα, ERβ, and prolactin expression in the pituitary gland compared to the solvent only group, while the estradiol group showed higher levels. Serum prolactin levels were similar between the 4HR and solvent only groups. In one study, 4-hexylresorcinol increased theshelf lifeofshrimpby reducingmelanosis(black spots). In mice with cancer, 4-hexylresorcinol inhibitedNF-κBand extended their survival rate.