This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.
Zopiclone is a sleep-promoting and sedative agent from the Z-drug class used for the treatment of insomnia. Its effects are based on binding to the GABAA receptor. The tablets are taken immediately before bedtime. Due to possible adverse effects and the potential for dependence, the medicinal product should only be administered short-term and with restraint. Zopiclone is metabolized by CYP3A4. Possible adverse effects include, among others, gastrointestinal disturbances, psychiatric disorders, dependence, and withdrawal symptoms.
Zopiclone (ATC N05CF01) has sleep-promoting, sedative, anticonvulsant, and muscle-relaxant properties. As with benzodiazepines, its effects are based on binding to the GABAA receptor, although zopiclone has no obvious structural similarities with this drug class. Unlike the other Z-drugs, zopiclone has a relatively long half-life of 5 hours.
Mechanism of action of the Z-drugs, click to enlarge. Illustration © PharmaWiki
