Pharmacotherapeutic group: prolactin inhibitors (ATC code G02C B04)
Quinagolide, the active ingredient of NORPROLAC, is a selective dopamine D
2
-receptor agonist not belonging to the chemical classes of ergot or ergoline compounds. Owing to its dopaminergic action, the drug exerts a strong inhibitory effect on the secretion of the anterior pituitary hormone prolactin, but does not reduce normal levels of other pituitary hormones. In some patients the reduction of prolactin secretion may be accompanied by short- lasting, small increases in plasma growth hormone levels, the clinical significance of which is unknown.
As a specific inhibitor of prolactin secretion with a prolonged duration of action, NORPROLAC has been shown to be effective and suitable for once-a- day oral treatment of patients presenting with hyperprolactinaemia and its clinical manifestations such as galactorrhoea, oligomenorrhoea, amenorrhoea, infertility and reduced libido.
