What is BUSULFEX used for?

( ARTG ) Busulfex is indicated for use in combination with cyclophosphamide, melphalan or fludarabine in conditioning prior to haematopoietic stem cell transplantation.

How does BUSULFEX work?

EUEMA:by INNUSDailyMed:BusulfanUSFDA:Busulfan AU:D L01AB01(WHO) AU:S4(Prescription only)CA:℞-onlyUK:POM(Prescription only)US:℞-onlyEU:Rx-only Butane-1,4-diyl dimethanesulfonate 55-98-1Y 2478 7136 DB01008Y 2384Y G1LN9045DK D00248Y CHEBI:28901Y ChEMBL820Y DTXSID3020910 Interactive image CS(=O)(=O)OCCCCOS(=O)(=O)C InChI=1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3YKey:COVZYZSDYWQREU-UH

What pharmaceutical form is BUSULFEX available in?

BUSULFEX: INJECTION 6 mg/mL (INTRAVENOUS)

What are the side effects of BUSULFEX?

You can help ensure medicines are safe by reporting the side effects you experience. You can report side effects to your doctor, or directly at www.tga.gov.au/reporting-problems

Does BUSULFEX interact with other medications?

Busulfan is metabolized viaglutathioneconjugation in the liver to inactivemetabolites.Itraconazolecan decrease busulfan clearance by up to 25%, resulting in AUC levels >1500 micromolxmin and increased risk of hepatic VOD. Concomitant use ofacetaminophenwithin 72 hours of busulfan use can reduce busulfan clearance (resulting in increased busulfan AUC), asacetaminophenis also metabolized viaglutathioneand may deplete stores.Phenytoinincreases hepatic clearance of busulfan (resulting in decreased

Can BUSULFEX be used during pregnancy?

( AHT ) For the active ingredient busulfan You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

Who manufactures BUSULFEX?

Otsuka America Pharmaceutical, Inc.

What ATC class does BUSULFEX belong to?

BUSULFEX: ATC L01AB01. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

OTC

BUSULFEX

6 mg/mL, Injection

INN: BUSULFAN

Data updated: 2026-05-14

Available in:

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Form

INJECTION

Dosage

6 mg/mL

Route

INTRAVENOUS

Storage

—

About This Product

Manufacturer

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