What is LIDOCAINE HYDROCHLORIDE used for?

Absolute contraindications for the use of lidocaine include: Heart block, second or third degree (without pacemaker)Severesinoatrial block(without pacemaker)Seriousadverse drug reactionto lidocaine or amide local anestheticsHypersensitivity to corn and corn-related products (corn-derived dextrose is used in the mixed injections)Concurrent treatment withquinidine,flecainide,disopyramide,procainamide(class I antiarrhythmic agents)Prior use ofamiodarone hydrochlorideAdams–Stokes syndro

What pharmaceutical form is LIDOCAINE HYDROCHLORIDE available in?

LIDOCAINE HYDROCHLORIDE: GEL 20 mg/g (TOPICAL)

What are the side effects of LIDOCAINE HYDROCHLORIDE?

Adverse drug reactions(ADRs) are rare when lidocaine is used as a local anesthetic and is administered correctly. Most ADRs associated with lidocaine for anesthesia relate to administration technique (resulting in systemic exposure) or pharmacological effects of anesthesia, andallergicreactions only rarely occur.Systemic exposure to excessive quantities of lidocaine mainly results incentral nervous system(CNS) andcardiovasculareffects – CNS effects usually occur at lowerblood p

Does LIDOCAINE HYDROCHLORIDE interact with other medications?

Any drugs that are alsoligandsofCYP3A4andCYP1A2can potentially increase serum levels and potential for toxicity or decrease serum levels and the efficacy, depending on whether they induce or inhibit the enzymes, respectively. Drugs that may increase the chance ofmethemoglobinemiashould also be considered carefully.Dronedaroneandliposomalmorphineare both absolutely acontraindication, as they may increase the serum levels, but hundreds of other drugs require monitoring for intera

What ATC class does LIDOCAINE HYDROCHLORIDE belong to?

LIDOCAINE HYDROCHLORIDE: ATC C01BB01. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

LIDOCAINE HYDROCHLORIDE

This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.

LIDOCAINE HYDROCHLORIDE — Description, Dosage, Side Effects | PillsCard

SystemicMonograph USDailyMed:Lidocaine AU:A C01BB01(WHO)C05AD01(WHO)D04AB01(WHO)N01BB02(WHO)N01BB52(WHO)R02AD02(WHO)S01HA07(WHO)S02DA01(WHO)QC01BB01(WHO)QC05AD01(WHO)QD04AB01(WHO)QN01BB02(WHO)QN01BB52(WHO)QR02AD02(WHO)QS01HA07(WHO)QS02DA01(WHO)QD04AB51(WHO) AU:S5, S4, and S2CA:℞-onlyUK:GSL, P, and POMUS:OTC/ Rx-only 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide 137-58-6Yas HCl:73-78-9 3676as HCl:6314 2623 DB00281Yas HCl:DBSALT001508 3548Yas HCl:6075 98PI200987as HCl:EC2CNF7XFP D00358Yas HCl:D02086Y CHEBI:6456Yas HCl:CHEBI:50512 ChEMBL79Yas HCl:ChEMBL541521 LQZ (PDBe,RCSB PDB) DTXSID1045166 Interactive image Cc1cccc(C)c1NC(=O)CN(CC)CC InChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)YKey:NNJVILVZKWQKPM-UHFFFAOYSA-NY Li‍‍‍‍‍‍‍‍‍‍‍‍‍docaine, also known aslignocaineand sold under the brand nameXylocaineamong others, is alocal anestheticof theaminoamidetype.It is also used to treatventricular tachycardiaandventricular fibrillation.When used for local anaesthesia or in nerve blocks, lidocaine typically begins working within several minutes and lasts for half an hour to three hours.Lidocaine mixtures may also be applied directly to the skin ormucous membranesto numb the area.It is often used mixed with a small amount ofadrenaline(epinephrine) to prolong its local effects and to decrease bleeding. If injected intravenously, it may cause cerebral effects such as confusion, changes in vision, numbness, tingling, and vomiting.It can causelow blood pressureand an irregular heart rate.There are concerns that injecting it into a joint can cause problems with thecartilage.It appears to be generally safe for use inpregnancy.A lower dose may be required in those with liver problems.It is generally safe to use in those allergic totetracaineorbenzocaine.Lidocaine is anantiarrhythmic medicationof the class Ib type.This means it works byblocking sodium channelsthus decreasing the rate of contractions of the heart.When injected near nerves, the nerves cannot conduct signals to or fromthe brain. Lidocaine was discovered in 1946 and went on sale in 1948.It is on theWorld Health Organization's List of Essential Medicines.It is available as ageneric medication.In 2023, it was the 277th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.

LIDOCAINE HYDROCHLORIDE

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