FLUTICASONE PROPIONATE

USDailyMed:Fluticasone propionate AU:B3 D07AC17(WHO)R01AD08(WHO)R03BA05(WHO)R01AD58(WHO) AU:S4(Prescription only)CA:℞-onlyUK:P (Pharmacy medicines) /POM(Prescription)US:OTC/Rx-only S-(fluoromethyl)-6α,9-difluoro-11β, 17-dihydroxy-16α-methyl-3-oxoandrosta-1, 4-diene-17β-carbothioate, 17-propanoate 80474-14-2Y 444036 7080 DB00588Y 392059Y O2GMZ0LF5W D01708 CHEBI:31441Y ChEMBL1473Y DTXSID8045511 Interactive image CCC(=O)OC1(C(CC2C1(CC(C3(C2CC(C4=CC(=O)C=CC43C)F)F)O)C)C)C(=O)SCF InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(‍‍‍‍‍‍​​​‍​​​​​​27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1YKey:WMWTYOKRWGGJOA-CENSZEJFSA-NY Fluticasone propionate, sold under the brand namesFloventandFlonaseamong others, is aglucocorticoidsteroidmedication.When inhaled it is used for the long term management ofasthmaandchronic obstructive pulmonary disease(COPD).In the nose it is used forhay feverandnasal polyps.It can also be used formouth ulcers. Common side effects when inhaled includeupper respiratory tract infections,sinusitis,thrush, andcough.Common side effects when used in the nose includenosebleedingandsore throat.Unlikefluticasone furoate, which is approved in children as young as two years of age when used for allergies, fluticasone propionate is only approved for children four years and older. Fluticasone propionate was patented in 1980, and approved for medical use in 1990.It is available as ageneric medication.In 2023, fluticasone was the 26th most commonly prescribed medication in the United States, with more than 21million prescriptions.