DEXTROMETHORPHAN HYDROBROMIDE; GUAIFENESIN

USDailyMed:Guaifenesin R05CA03(WHO)QM03BX90(WHO) NZ:OTCUS:OTC/ Rx-only (RS)-3-(2-methoxyphenoxy)propane-1,2-diol 93-14-1Y 3516 7617 DB00874Y 3396Y 495W7451VQ D00337Y ChEMBL980Y DTXSID5023114 Interactive image O(c1ccccc1OC)CC(O)CO InChI=1S/C10H14O4/c1-13-9-4-2-3-5-10(9)14-7-8(12)6-11/h2-5,8,11-12H,6-7H2,1H3YKey:HSRJKNPTNIJEKV-UHFFFAOYSA-NY Guaifenesin, also known asglyceryl guaiacolate, sold under the brand nameMucinex, among others,is anexpectorantmedication taken by mouth and marketed as an aid to eliminatesputumfrom therespiratory tract.​​​‍​​‍​​​​‍​​‍‍ Chemically, it is anetherofguaiacolandglycerine. It may be used in combination with other medications.A 2014 study found that guaifenesin does not affect sputum volume in upper respiratory infections (the upper respiratory system includes most breathing parts above the lungs).In 2023, it was alleged to work by making airway secretions more liquid. Side effects may includedizziness,sleepiness,skin rash, andnausea.While it has not been properly studied in pregnancy, it appears to be safe. Guaifenesin has been used medically since at least 1933.It is available as ageneric medicationandover-the-counter(OTC).In 2023, it was the 291st most commonly prescribed medication in the United States, with more than 500,000 prescriptions.In 2023, the combination dextromethorphan/guaifenesin was the 315th most commonly prescribed medication in the United States, with more than 200,000 prescriptions.