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A02BA03
Source
OPENFDA_NDC
USDailyMed:Famotidine
AU:B1
A02BA03(WHO)
AU:S3(Pharmacist only) / S4UK:POM(Prescription only)US:OTC/Rx-only
3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N-sulfamoylpropanimidamide
76824-35-6Y
3325
7074
DB00927Y
3208Y
5QZO15J2Z8
D00318Y
CHEBI:4975Y
ChEMBL902Y
FO9 (PDBe,RCSB PDB)
DTXSID5023039
Interactive image
NS(=O)(=O)/N=C(\N)CCSCc1csc(n1)N=C(N)N
InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)YKey:XUFQPHANEAPEMJ-UHFFFAOYSA-NY
Famotidine, sold under the brand namePepcidamong others, is ahistamine H2receptor antagonistmedication that decreasesstomach acidproduction.It is used to treatpeptic ulcer disease,gastroesophageal reflux disease, andZollinger–Ellison syndrome.It is takenby mouthor byinjection into a vein.It begins working within an hour.
Common side effects includeheadache,abdominal pain,diarrheaorconstipation, anddizziness.Serious side effects may includepneumoniaandseizures.Use inpregnancyappears safe but has not been well studied, while use duringbreastfeedingis not recommended.
Famotidine was patented in 1979 and came into medical use in 1985.It is available as ageneric medication.In 2023, it was the 33rd most commonly prescribed medication in the United States, with more than 16million prescriptions.