AZELAIC ACID

USDailyMed:Azelaic acid DTXSID8021640 123-99-9Y Interactive image CHEBI:48131Y ChEMBL1238Y 2179Y DB00548Y 204-669-1 7484 D03034Y 2266 F2VW3D43YTY DTXSID8021640 InChI=1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)YKey: BDJRBEYXGGNYIS-UHFFFAOYSA-NYInChI=1/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)Key: BDJRBEYXGGNYIS-UHFFFAOYAK O=C(O)CCCCCCCC(=O)O AU:S5(Caution) /Schedule 4, Schedule 2 Appendix E, clause 3 Appendix F, clause 4US:℞-only Azelaic acid(AzA), or nonanedioic acid, is anorganic compoundwith the formula HOOC(CH2)7COOH.This saturateddicarboxylic acidexists as a white powder. It is found inwheat,rye, andbarley. It is a precursor to diverse industrial products including polymers and plasticizers, as well as being a component of several hair and skin conditioners.In medicine, topical formulations of AzA are used in the treatment ofacne vulgaris, where they exertantimicrobialandkeratolyticeffects that reduceclogged hair folliclesand inflammation.In plants, AzA functions as a mobile signaling molecule that primessystemic acquired resistanceagainst pathogens by inducing the accumulation ofsalicylic acid.AzA also inhibitstyrosinase.