Reviews reflect personal experiences and are not medical advice. Always consult your doctor.
Manufacturer
ADVANCED RX PHARMACY OF TENNESSEE, LLC
ATC Code
J01MA01
Source
OPENFDA_NDC
USDailyMed:Levofloxacin
J01MA12(WHO)S01AE05(WHO)A02BD10(WHO)J01RA05(WHO)
CA:℞-onlyUS:℞-onlyEU:Rx-onlyIn general: ℞ (Prescription only)
(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
100986-85-4Y
149096
DB01137Y
131410Y
RIX4E89Y14
D08120YC07660
CHEBI:63598
ChEMBL33Y
002307
LFX (PDBe,RCSB PDB)
DTXSID0041060
Interactive image
C[C@H]1COc2c3n1cc(c(=O)c3cc(c2N4CCN(CC4)C)F)C(=O)O
InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1YKey:GSDSWSVVBLHKDQ-JTQLQIEISA-NY
Levofloxacin, sold under the brand nameLevaquinamong others, is abroad-spectrum antibioticof thefluoroquinolonedrug class.It is theleft-handed isomerof the medicationofloxacin.It is used to treat a number ofbacterial infectionsincludingacute bacterial sinusitis,pneumonia,H. pylori(in combination with other medications),urinary tract infections,Legionnaires' disease,chronic bacterial prostatitis, and some types ofgastroenteritis.Along with other antibiotics it may be used to treattuberculosis,meningitis, orpelvic inflammatory disease.It is available by mouth,intravenously,and ineye dropform.
Common side effects includenausea,diarrhea, and trouble sleeping.A warning concerning all fluoroquinolones was issued in 2016: "An FDA safety review has shown that fluoroquinolones when used systemically (i.e. tablets, capsules, and injectable) are associated with disabling and potentially permanent serious adverse effects that can occur together. These adverse effects can involve the tendons, muscles, joints, nerves, and central nervous system."
Other serious side effects may includetendon rupture,tendon inflammation,seizures,psychosis, and potentially permanentperipheral nerve damage.Tendon damage may appear months after treatment is completed.People may alsosunburn more easily.In people withmyasthenia gravis, muscle weakness and breathing problems may worsen.While use during pregnancy is not recommended, risk appears to be low.The use of other medications in this class appear to be safe whilebreastfeeding; however, the safety of levofloxacin is unclear.
Levofloxacin was patented in 1985 and approved for medical use in the United States in 1996.It is on theWorld Health Organization's List of Essential Medicines.It is available as ageneric medication.In 2023, it was the 231st most commonly prescribed medication in the United States, with more than 1million prescriptions.
⚠️ Warnings
•Two hours time interval should be there in between antacids, didanosine and to this medication.
• It may cause dizziness, tiredness. Do not drive a car, operate machinery while taking this medication.
• It may make your skin sensitive to sunlight.
Caution should be exercised in patients with history of prolonged QT interval, irregular heartbeat, nerve problems, low level of potassium in your blood, slow heartbeat, thickening and hardening of the walls of the arteries in the brain, seizures, chest pain or liver disease.
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Pediatric patients may develop with increased risk of musculoskeletal disorders; consult with your healthcare provider about this
.