VALGANCICLOVIR HYDROCHLORIDE

USDailyMed:Valganciclovir AU:D J05AB14(WHO) AU:S4(Prescription only)UK:POM(Prescription only)US:℞-only 2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]-3-hydroxypropyl-(2S)-2-amino-3-methylbutanoate 175865-60-8Y 135413535 4716 DB01610Y 57721Y GCU97FKN3R D02495as HCl:D03256 ChEMBL1201314N 032967 F9E (PDBe,RCSB PDB) DTXSID8048288 Interactive image O=C(OCC(OCn1c2N\C(=N/C(=O)c2nc1)N)CO)[C@@H](N)C(C)C InChI=1S/C14H22N6O5/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-1‍‍‍‍‍‍​​​‍​​​​​​7-10-11(20)18-14(16)19-12(10)22/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22)/t8?,9-/m0/s1YKey:WPVFJKSGQUFQAP-GKAPJAKFSA-NY Valganciclovir, sold under the brand nameValcyteamong others, is anantiviral medicationused to treatcytomegalovirus (CMV) infectionin those withHIV/AIDSor followingorgan transplant.It is often used long term as it only suppresses rather than cures the infection.Valganciclovir is taken by mouth. Common side effects includeabdominal pain, headaches, trouble sleeping, nausea, fever, andlow blood cell counts.Other side effects may includeinfertilityandkidney problems.When used duringpregnancy, it causes birth defects in some animals.Valganciclovir is theL-valylesterofganciclovirand works when broken down into ganciclovir by theintestineandliver. Valganciclovir was approved for medical use in 2001.It is on theWorld Health Organization's List of Essential Medicines.In 2017, ageneric versionwas approved.