Tobramycin

USDailyMed:Tobramycin AU:D J01GB01(WHO)S01AA12(WHO) AU:S4(Prescription only)CA:℞-onlyUK:POM(Prescription only)US:℞-onlyEU:Rx-onlyIn general: ℞ (Prescription only) (2S,3R,4S,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol 32986-56-4Y 36294 DB00684Y 33377Y VZ8RRZ51VK D00063YC00397Y CHEBI:28864Y ChEMBL1747Y TOY (PDBe,RCSB PDB) DTXSID8023680 Interactive image C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H](C[C@@H]([C@H](O3)CN)O)N)N InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1YKey:NLVFBUXFDBBNBW-PBSUHMDJSA-NY Tobramycinis anaminoglycosideantibioticderived fromStreptomyces tenebrariusthat is used to treat various types ofbacterialinfections, particularlyGram-negativeinfections. It is especially effective against species ofPseudomonas. It was patented in 1965, and approved for medical use in 1974.It is on theWorld Health Organization's List of Essential Medicines.In 2023, it was the 298th most commonly prescribed medication in the United States, with more than 400,000 prescriptions.