BiEST 5.0 Estrogen Cream - 3.6oz

G03CA04(WHO)G03CC06(WHO) In general: ℞ (Prescription only) (8R,9S,13S,14S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol 50-27-1Y1306-04-3514-68-1 (succinate) 5756 2821 DB04573Y 5553Y FB33469R8E C05141Y CHEBI:27974Y ChEMBL193482Y Interactive image Oc1ccc2[C@H]3CC[C@]4(C)[C@]5([C@@]6C[C@H]4[C@@H]3CCc2c1).O6.O5 InChI=1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1YKey:PROQIPRRNZUXQM-ZXXIGWHRSA-NY Estriol(E3), sold under the brand nameOvestinamong others, is anestrogenmedication andnaturally occurringsteroid hormonewhich is used inmenopausal hormone therapy.It is also used inveterinary medicineasIncurinto treaturinary incontinencedue toestrogen deficiencyin dogs.The medication is takenby mouthin the form oftablets, as acreamthat isapplied to the skin, as a cream orpessarythat isapplied in the vagina, and byinjection into muscle. Estriol is well-toleratedand produces relatively fewadverse effects.Side effects may includebreast tenderness,vaginal discomfortanddischarge, andendometrial hyperplasia.Estriol is anaturally occurringandbioidenticalestrogen, or anagonistof theestrogen receptor, thebiological targetofestrogenslikeendogenousestradiol.It is an atypical and relatively weak estrogen, with much lowerpotencythanestradiol.When present continuously at adequate concentrations however, estriol produces fullestrogeniceffects similarly to estradiol. Estriol was first discovered in 1930,and was introduced for medical use shortly thereafter.Estriol esterssuch asestriol succinateare also used.Although it is less commonly employed than other estrogens like estradiol andconjugated estrogens, estriol is widely available for medical use inEuropeand elsewhere throughout the world.