What is PERJETA used for?

1 INDICATIONS AND USAGE PERJETA is a HER2/neu receptor antagonist indicated for: Use in combination with trastuzumab and docetaxel for treatment of adults with HER2-positive metastatic breast cancer (MBC) who have not received prior anti-HER2 therapy or chemotherapy for metastatic disease. ( 1.1 ) Use in combination with trastuzumab and chemotherapy as neoadjuvant treatment of adults with HER2-positive, locally advanced, inflammatory, or early stage breast cancer (either greate

How does PERJETA work?

11 DESCRIPTION Pertuzumab is a recombinant humanized monoclonal antibody and HER2/neu receptor antagonist that targets the extracellular dimerization domain (Subdomain II) of the human epidermal growth factor receptor 2 protein (HER2).

What is the active ingredient in PERJETA?

Trastuzumabum + Pertuzumabum (Pertuzumabum, Trastuzumabum)

What pharmaceutical form is PERJETA available in?

PERJETA: Roztwór do wstrzykiwań 600 mg + 1200 mg (podskórna)

Is PERJETA OTC or prescription only?

PERJETA requires a doctor's prescription.

What are the side effects of PERJETA?

6 ADVERSE REACTIONS The following adverse reactions are discussed in greater detail in other sections of the label: Left Ventricular Dysfunction [see Warnings and Precautions (5.1) ] Embryo-Fetal Toxicity [see Warnings and Precautions (5.2) ] Infusion-Related Reactions [see Warnings and Precautions (5.3) ] Hypersensitivity Reactions/Anaphylaxis [see Warnings and Precautions (5.4) ] Metastatic Breast Cancer The most common adverse reactions (> 30%) with PERJETA in combination with trastuzumab and

Who should NOT take PERJETA?

4 CONTRAINDICATIONS PERJETA is contraindicated in patients with known hypersensitivity to pertuzumab or to any of its excipients [see Warnings and Precautions (5.4)]. PERJETA is contraindicated in patients with known hypersensitivity to pertuzumab or to any of its excipients. ( 4 )

Can PERJETA be used during pregnancy?

8 USE IN SPECIFIC POPULATIONS Females and Males of Reproductive Potential: Verify the pregnancy status of females prior to initiation of PERJETA. ( 8.3 ) 8.1 Pregnancy Pregnancy Pharmacovigilance Program There is a pregnancy pharmacovigilance program for PERJETA. If PERJETA is administered during pregnancy, or if a patient becomes pregnant while receiving PERJETA or within 7 months following the last dose of PERJETA in combination with trastuzumab, health care providers and pat

What precautions should be taken with PERJETA?

• Caution should be exercised in patients with liver or kidney impairment, during pregnancy and breastfeeding. • Patient may develop with increased risk of ventricular dysfunction; monitor heart function regularly while taking this medication. • It may cause harm to fetus when it is administered to pregnant women; consult with your healthcare provider before taking this medication.

Who manufactures PERJETA?

Roche Registration GmbH (Niemcy)

What ATC class does PERJETA belong to?

PERJETA: ATC L01FY01. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

PERJETA

600 mg + 1200 mg, Roztwór do wstrzykiwań

INN: Trastuzumabum + Pertuzumabum

Data updated: 2026-04-13

Available in:

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Form

Roztwór do wstrzykiwań

Dosage

600 mg + 1200 mg

Route

podskórna

Storage

Storage and Handling Store vials refrigerated at 2°C to 8°C (36°F‍‍‍‍‍‍‍ to 46°F) in the original carton until time of use to protect from light. Do not freeze. Do not shake. DO NOT FREEZE. DO NOT SHAKE.

User Reviews

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