Tizanidine Hydrochloride

USDailyMed:Tizanidine M03BX02(WHO) UK:POM(Prescription only)US:℞-only 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)benzo[c][1,2,5]thiadiazol-4-amine 51322-75-9Y 5487 DB00697Y 5287Y 6AI06C00GW D08611Yas HCl:D00776Y ChEMBL1079Y DTXSID9023679 Interactive image Clc1ccc3nsnc3c1NC/2=N/CCN\2 InChI=1S/C9H8ClN5S/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9/h1-2H,3-4H2,(H2,11,12,13)YKey:XFYDIVBRZNQMJC-UHFFFAOYSA-NY Tizanidine, sold under the brand nameZanaflexamong others, is analpha-2 (α2) adrenergic receptoragonist,similar toclonidine, that is used to treatmuscle spasticitydue tospinal cord injury,multiple sclerosis, andspastic cerebral palsy.Effectiveness appears similar tobaclofenordiazepam.It is takenby mouth. Common side effects of tizanidine includedry mouth,sleepiness,weakness, anddizziness.Serious side effects may includelow blood pressure,liver problems,psychosis, andQT prolongation.It is unclear if use inpregnancyandbreastfeedingis safe.It is anα2-adrenergic agonist, but how it works is not entirely clear. Tizanidine was approved for medical use in the United States in 1996.It is available as ageneric medication.In 2023, it was the 81st most commonly prescribed medication in the United States, with more than 8million prescriptions.