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Form
INJECTION, SOLUTION
Dosage
150 mg/mL
Route
INTRAMUSCULAR, INTRAVENOUS
Storage
—
About This Product
Manufacturer
Pharmacia & Upjohn Company LLC
ATC Code
D10AF01
Source
OPENFDA_NDC
USDailyMed:Clindamycin
AU:A
J01FF01(WHO)D10AF01(WHO)G01AA10(WHO)D10AF51(WHO)
AU:S4(Prescription only)CA:℞-onlyUK:POM(Prescription only)US:℞-only
methyl 7-chloro-6,7,8-trideoxy-6-{[(4R)-1-methyl-4-propyl-L-prolyl]amino}-1-thio-L-threo-α-D-galacto-octopyranoside
18323-44-9Y
446598
DB01190Y
393915Y
3U02EL437C
D00277Yas HCl:D02132Y
CHEBI:3745N
ChEMBL1753N
CLY (PDBe,RCSB PDB)
DTXSID90928608
Interactive image
Cl[C@@H](C)[C@@H](NC(=O)[C@H]1N(C)C[C@H](CCC)C1)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O
InChI=1S/C18H33ClN2O5S/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25)/t9-,10+,11-,12+,13-,14+,15+,16+,18+/m0/s1YKey:KDLRVYVGXIQJDK-AWPVFWJPSA-NY
Clindamycinis alincosamideantibioticmedication used for the treatment of a number ofbacterial infections, includingosteomyelitis(bone) orjoint infections,pelvic inflammatory disease,strep throat,pneumonia,acute otitis media(middle ear infections), andendocarditis.It can also be used to treatacne,and some cases ofmethicillin-resistantStaphylococcus aureus(MRSA).In combination withquinine, it can be used to treatmalaria.It is available by mouth, byinjection into a vein, and as a cream or a gel to be applied to the skin or in the vagina.
Common side effects include nausea and vomiting, diarrhea, skin rashes, and pain at the site of injection.It increases the risk of hospital-acquiredClostridioides difficilecolitisabout fourfold and thus is only recommended for use when other antibiotics are not appropriate.It appears to be generally safe in pregnancy.It is of thelincosamide classand works by blocking bacteria from making protein.
Clindamycin was first made in 1966 fromlincomycin.It is on theWorld Health Organization's List of Essential Medicines.It is available as ageneric medication.In 2023, it was the 149th most commonly prescribed medication in the United States, with more than 3million prescriptions.