Doxorubicin Hydrochloride

EUEMA:by INNUSDailyMed:Doxorubicin AU:D L01DB01(WHO) AU:S4(Prescription only)CA:℞-onlyUK:POM(Prescription only)US:℞-onlyEU:Rx-onlyIn general: ℞ (Prescription only) (7S,9S)-7-[(2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 23214-92-8Yas HCl:25316-40-9 31703as HCl:443939 7069 DB00997Yas HCl:DBSALT000060 29400Yas HCl:391993 80168379AGas HCl:82F2G7BL4E D03899Yas HCl:D01275 CHEBI:28748Yas HCl:CHEBI:31522 ChEMBL53463Nas HCl:ChEMBL359744 DTXSID8021480 Interactive image C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](Cc3c2c(c4c(c3O)C(=O)c5cccc(c5C4=O)OC)O)(C(=O)CO)O)N)O InChI=1S/C27H29NO‍‍‍‍‍‍​​​‍​​​​​​11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27 (36,16(30)9–29)7-12-19(15)26(35)21–20(24(12)33)23 (32)11-4-3-5-14(37–2)18(11)25(21)34/h3-5,10,13,15, 17,22,29,31,33,35-36H,6–9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1NKey:AOJJSUZBOXZQNB-TZSSRYMLSA-NY Doxorubicin, sold under the brand nameAdriamycinamong others, is achemotherapy medicationused to treatcancer.This includesbreast cancer,bladder cancer,Kaposi's sarcoma,lymphoma, andacute lymphocytic leukemia.It is often usedtogether with other chemotherapy agents.Doxorubicin is given byinjection into a vein. Common side effects includehair loss,bone marrow suppression,vomiting, rash, andinflammation of the mouth.Other serious side effects may includeallergic reactionssuch asanaphylaxis,heart damage, tissue damage at the site of injection,radiation recall, and treatment-relatedleukemia.People often experience red discoloration of the urine for a few days.Doxorubicin is in theanthracyclineandantitumor antibioticfamily of medications.It works in part by interfering with the function ofDNA. Doxorubicin was approved for medical use in the United States in 1974.It is on theWorld Health Organization's List of Essential Medicines.Versions that arepegylatedand inliposomesare also available; however, they are more expensive.Doxorubicin was originally made from the bacteriumStreptomyces peucetius.