What is NICOTINE used for?

Nicotine use for tobacco cessation has few contraindications. It is not known whether nicotine replacement therapy is effective for smoking cessation in adolescents, as of 2014.It is therefore not recommended to adolescents.It is not safe to use nicotine during pregnancy or breastfeeding, although it is safer than smoking. The desirability of NRT use in pregnancy is therefore debated. Randomized trials and observational studies of nicotine replacement therapy in cardiovascular

What pharmaceutical form is NICOTINE available in?

NICOTINE: LOZENGE 2 mg/1 (ORAL)

What are the side effects of NICOTINE?

Nicotine is classified as a poison,and it is "extremely hazardous".The CDC says it is "toxic to developing fetuses and is a health danger for pregnant women." It can harm brain development up to age twenty-five, and early use of nicotine can predispose young people to smoking and drug use.However, at doses typically used by consumers, it presents little if any hazard to adult users.Although at low amounts nicotine has a mildanalgesiceffect,at sufficiently high doses nicotine ma

Can NICOTINE be used during pregnancy?

Nicotine has been shown to produce birth defects in some animal species, but not others;consequently, it is considered to be a possibleteratogenin humans.Inanimal studiesthat resulted in birth defects, researchers found that nicotine negatively affects fetalbrain developmentand pregnancy outcomes;the negative effects on early brain development are associated with abnormalities inbrain metabolismandneurotransmitter systemfunction.Nicotine crosses theplacentaand is found in the b

What ATC class does NICOTINE belong to?

NICOTINE: ATC N07BA01. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

NICOTINE

This information is for educational purposes only. It is not intended as medical advice. Always consult a qualified healthcare professional.

NICOTINE — Description, Dosage, Side Effects | PillsCard

AU:D N07BA01(WHO)QP53AX13(WHO) AU:S7(Dangerous drug)BR:UnscheduledCA: UnscheduledDE: UnscheduledNZ: UnscheduledUK:General sales list(GSL, OTC)US:OTCandprescriptionUN:UnscheduledEU:Unscheduled / OTCSE: Unscheduled / OTC Inhalation: 80–90%Intranasal: 60–80%Transdermal: 68–100% 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine 54-11-5Y 89594 2585 DB00184Y 80863Y 6M3C89ZY6R D03365Y CHEBI:18723Y ChEMBL3Y NCT (PDBe,RCSB PDB) DTXSID1020930 Interactive image c1ncccc1[C@@H]2CCCN2C InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1YKey:SNICXCGAKADSCV-JTQLQIEISA-NY Nicotiana(Nicotiana tabacum)NicotineHealth effectsDiseasesTypes ArtHistoryControlPoliticsReligious viewsSmokingTobacco and other drugsTobacconist CultivationCuringIndustryMarketingProductsPrevalence of consumption vte Nicotineis analkaloidfound primarily in plants of thenightshadefamily, notably intobacco; it is alsosynthesized.Nicotine is usedrecreationallyfor itsstimulantandanxiolyticeffects.‍‍‍‍‍‍‍‍‍‍‍‍‍ In tobacco leaves, nicotine constitutes about 0.6–3.0% of the dry weight,and smaller, trace quantities occur in otherSolanaceaecrops such as tomatoes, potatoes, and eggplants. In pure form, nicotine is a colorless to yellowish, oily liquid that readily penetrates biological membranes and acts as a potentneurotoxinin insects, where it serves as anantiherbivoretoxin. Historically, it was widely used as aninsecticide, and its structure provided the basis for syntheticneonicotinoidpesticides. In humans, nicotine acts primarily as astimulantby binding to and activatingnicotinic acetylcholine receptors(nAChRs) in thecentral nervous systemand peripheral tissues. This results in the release ofneurotransmitterssuch asdopamine,acetylcholine, andnorepinephrine, producing effects including increased alertness, reduced anxiety, and mild euphoria.Nicotine is typically consumed throughtobacco smoking,vaping, or othernicotine delivery systems. An average cigarette yields about 2 mg of absorbed nicotine, a dose sufficient to produce reinforcement and dependence while remaining far below toxic levels. Nicotine is highly addictive, andnicotine dependenceis characterized bytolerance,physical dependence,psychological dependence, andnicotine withdrawalsymptoms such as irritability, anxiety, and difficulty concentrating.Nicotine replacement therapy(NRT) products, including gums, patches, and lozenges, deliver the compound in slower, lower doses that are less addictive and are used medically to help people quit smoking.Synthetic derivatives of nicotine, such asvarenicline, act as partial agonists at nicotinic receptors and are also used as smoking cessation aids. Nicotine itself is not classified as acarcinogenby either theInternational Agency for Research on Canceror theSurgeon General of the United States.At high doses it can causenicotine poisoningand respiratory paralysis. Chronic exposure may also affect theimmune,cardiovascular, andnervoussystems.Nicotine is also a knownteratogen, associated with adverse developmental effects during pregnancy,and mayimpair adolescent neurodevelopment, though the extent of this effect in humans remains debated.

NICOTINE

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