DOCUSATE SODIUM

USDailyMed:Docusate AU:A A06AA02(WHO) CA:OTCUK:General sales list(GSL, OTC)US:OTCIn general:Over-the-counter(OTC) 1,4-bis(2-ethylhexyloxy)-1,4-dioxobutane-2-sulfonic acid 10041-19-7as salt:577-11-7 11339as salt:23673837 DB11089as salt:DBSALT001500 10862as salt:10861 M7P27195AGas salt:F05Q2T2JA0 as salt:D00305 CHEBI:534as salt:CHEBI:4674 ChEMBL1477036as salt:ChEMBL1905872 DTXSID8022959 Interactive imageas salt:Interactive image CCCCC(CC)COC(=O)CC(C(=O)OCC(CC)CCCC)S(O)(=O)=Oas salt: [Na+].[O-]S(=O)(=O)C(C(=O)OCC(CC)CCCC)CC(=O)OCC(CC)CCCC InChI=1S/C20H38O7S/c1-5-9-11-16(7-3)14-26-19(21)13-18‍‍‍‍‍‍​​​‍​​​​​​(28(23,24)25)20(22)27-15-17(8-4)12-10-6-2/h16-18H,5-15H2,1-4H3,(H,23,24,25)Key:HNSDLXPSAYFUHK-UHFFFAOYSA-Nas salt: InChI=1S/C20H38O7S.Na/c1-5-9-11-16(7-3)14-26-19(21)13-18(28(23,24)25)20(22)27-15-17(8-4)12-10-6-2;/h16-18H,5-15H2,1-4H3,(H,23,24,25);/q;+1/p-1Key:APSBXTVYXVQYAB-UHFFFAOYSA-M Docusateis the common chemical and pharmaceutical name of theanionbis(2-ethylhexyl) sulfosuccinate, also commonly calleddioctyl sulfosuccinate(DOSS). Saltsof this anion, especiallydocusate sodium, are widely used inmedicineas an emollientlaxativeand asstool softeners, by mouth or rectally.Some studies state that docusate is not more effective than aplacebofor improving constipation.Other docusate salts with medical use include those ofcalciumandpotassium.Docusate salts are also used asfood additives,emulsifiers,dispersants, andwetting agents, among other uses. It is on theWorld Health Organization's List of Essential Medicines.In 2023, it was the 148th most commonly prescribed medication in the United States, with more than 3million prescriptions.In 2023, the combination withsennawas the 242nd most commonly prescribed medication in the United States, with more than 1million prescriptions.