Brompheniramine

AU:A R06AB04(WHO) AU:S3(Pharmacist only)UK:P (Pharmacy medicines)US:OTCCN:OTC 3-(4-Chlorophenyl)-N,N-dimethyl-3-(pyridin-2-yl)-propan-1-amine 132-22-9Y 2725 1210 DB01114Y 2624Y 3U6IO1965U D07398Y CHEBI:52010Y ChEMBL505Y DTXSID0022804 Interactive image Clc1ccc(cc1)C(c2ncccc2)CCN(C)C InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3YKey:SOYKEARSMXGVTM-UHFFFAOYSA-NY Chlorphenamine(CP,CPM), also known aschlorpheniramine, is anantihistamineused to treat the symptoms ofallergic conditionssuch asallergic rhinitis(hay fever).It is takenorally(by mouth).The medication takes effect within two hours and lasts for about 4–6 hours.It is afirst-generation antihistamineand works by blocking thehistamine H1receptor. Common side effects include sleepiness, restlessness, and weakness. Other side effects may includedry mouthand wheeziness. Chlorpheniramine was patented in 1948 and came into medical use in 1949.It is available as ageneric medicationandover the counter. In 2023, it was the 318th most commonly prescribed medication in the United States, with more than 200,000 prescriptions.