Q: Can PHENTERMINE HYDROCHLORIDE; TOPIRAMATE be used during pregnancy?

Phentermine and topiramate can cause fetal harm. Data from pregnancy registries and epidemiology studies indicate that a fetus exposed to topiramate in the first trimester of pregnancy has an increased risk of oral clefts (cleft lip with or without cleft palate).If a patient becomes pregnant while taking phentermine/topiramate ER, treatment should be discontinued immediately, and the patient should be apprised of the potential hazard to a fetus. Females of reproductive potentia

Question 1

What is PHENTERMINE HYDROCHLORIDE; TOPIRAMATE used for?

Accepted Answer

Phentermine/topiramate ER is contraindicated in pregnancy, glaucoma, hyperthyroidism, during or with﻿‍​‍‍‍​‍‍‍‍‍‍‍‍​‍﻿in 14 days of taking monoamine oxidase inhibitors, and in patients with hypersensitivity or idiosyncrasy tosympathomimeticamines. Phentermine/topiramate ER can cause an increase in resting heart rate.

Question 2

How does PHENTERMINE HYDROCHLORIDE; TOPIRAMATE work?

Accepted Answer

A08AA51(WHO)QA08AA51(WHO)
US:Schedule IVIn general: ℞ (Prescription only)
960078-81-3
56842108
D11710
DTXSID20242081
Phentermine/topiramate, sold under the brand nameQsymia, is acombination drugofphentermineandtopiramateused to treatobesity.

Question 3

What is the active ingredient in PHENTERMINE HYDROCHLORIDE; TOPIRAMATE?

Accepted Answer

PHENTERMINE HYDROCHLORIDE; TOPIRAMATE

Question 4

What pharmaceutical form is PHENTERMINE HYDROCHLORIDE; TOPIRAMATE available in?

Accepted Answer

PHENTERMINE HYDROCHLORIDE; TOPIRAMATE: CAPSULE, EXTENDED RELEASE EQ 3.75MG BASE;23MG (ORAL)

Question 5

What are the side effects of PHENTERMINE HYDROCHLORIDE; TOPIRAMATE?

Accepted Answer

In clinical trials, the most common adverse events which occurred at a rate ≥5% and ≥1.5 times placebo included paraesthesia (tingling in fingers/toes), dizziness,altered taste,insomnia,constipation, anddry mouth.
In the US, the dru﻿‍​‍‍‍​‍‍‍‍‍‍‍‍​‍﻿g label contains warnings for increased heart rate, suicidal behavior and ideation, glaucoma, mood and sleep disorders, creatinine elevation, and metabolic acidosis.  Some of these warnings are based on historical observations in epilepsy patients ta

Question 6

Can PHENTERMINE HYDROCHLORIDE; TOPIRAMATE be used during pregnancy?

Accepted Answer

Phentermine and topiramate can cause fetal harm.﻿‍​‍‍‍​‍‍‍‍‍‍‍‍​‍﻿ Data from pregnancy registries and epidemiology studies indicate that a fetus exposed to topiramate in the first trimester of pregnancy has an increased risk of oral clefts (cleft lip with or without cleft palate).If a patient becomes pregnant while taking phentermine/topiramate ER, treatment should be discontinued immediately, and the patient should be apprised of the potential hazard to a fetus. Females of reproductive potentia

Question 7

What ATC class does PHENTERMINE HYDROCHLORIDE; TOPIRAMATE belong to?

Accepted Answer

PHENTERMINE HYDROCHLORIDE; TOPIRAMATE: ATC A08AA01. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

PHENTERMINE HYDROCHLORIDE; TOPIRAMATE

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