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• ♦ Caution should be exercised in patients with history of liver, kidney problems, high cholesterol, low blood platelet levels, diabetes, lung or breathing problems, any allergy, infections, who are taking other medications es‍​‍‍‍​‍‍‍‍‍‍‍‍​‍pecially for HIV or Hepatitis C , during pregnancy and breastfeeding. • Avoid contact with people who have infections. • Patient may develop with increased risk of progressive multifocal leukoencephalopathy (PML), severe kidney problems, certain types of cancer; if it is so consult with your doctor. • Avoid live vaccination while taking this medication. • It may affect blood sugar level; monitor sugar level regularly while taking this medication.