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OTC
BETAMETASONE
INN: BETAMETASONE
Data updated: 2026-06-02
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About This Product
ATC Code
S01CB04
Source
AIFA
USDailyMed:Betamethasone
AU:C
A07EA04(WHO)C05AA05(WHO)D07AC01(WHO)D07BC01(WHO)D07CC01(WHO)D07XC01(WHO)H02AB01(WHO)R01AD06(WHO)R03BA04(WHO)S01BA06(WHO)S01BB04(WHO)S01CA05(WHO)S01CB04(WHO)S02BA07(WHO)S03BA03(WHO)S03CA06(WHO)
AU:S4(Prescription only)UK:POM(Prescription only)US:℞-onlyIn general: ℞ (Prescription only)
(8S,9R,10S,11S,13S,14S,16S,17R)-9-Fluoro- 11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl- 6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro- 3H-cyclopenta[a]phenanthren-3-one
378-44-9Y
9782
7061
DB00443Y
9399Y
9842X06Q6M
D00244Y
CHEBI:3077Y
ChEMBL632Y
DTXSID3022667
Interactive image
O=C(CO)[C@]3(O)[C@]2(C[C@H](O)[C@]4(F)[C@@]/1(\C(=C/C(=O)\C=C\1)CC[C@H]4[C@@H]2C[C@@H]3C)C)C
InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1YKey:UREBDLICKHMUKA-DVTGEIKXSA-NY
Betamethasoneis asteroidmedication.It is used for a number of diseases includingrheumatic disorderssuch asrheumatoid arthritisandsystemic lupus erythematosus, skin diseases such asdermatitisandpsoriasis, allergic conditions such asasthmaandangioedema,preterm laborto speed the development of the baby's lungs,Crohn's disease, cancers such asleukemia, and along withfludrocortisoneforadrenocortical insufficiency, among others.It can be taken by mouth,injected into a muscle, or applied to the skin, typically in cream, lotion, or liquid forms.
Serious side effects include an increased risk of infection, muscle weakness,severe allergic reactions, andpsychosis.Long-term use may cause adrenal insufficiency.Stopping the medication suddenly following long-term use may be dangerous.The cream commonly results inincreased hair growthand skin irritation.Betamethasone belongs to theglucocorticoidclass of medication.It is astereoisomerofdexamethasone, the two compounds differing only in the spatial configuration of themethyl groupat position 16 (seesteroid nomenclature).
Betamethasone was patented in 1958, and approved for medical use in the United States in 1961.It is on theWorld Health Organization's List of Essential Medicines.It is available as ageneric medication.In 2023, it was the 280th most commonly prescribed medication in the United States, with more than 700,000 prescriptions.
Verified by medical editor
Kseniia Ozarchuk, MPharm · April 2026
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