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( ARTG ) BENLYSTA is indicated for:,add-on therapy for reducing disease activity in adult patients with active, autoantibody-positive systemic lupus erythematosus (SLE) with a high degree of disease activity (e.g.‍​‍‍‍​‍‍‍‍‍‍‍‍​‍ ANA titre greater than or equal to 1:80 and/or anti-dsDNA titre greater than or equal to 30 IU/mL) despite standard therapy.,treatment of active lupus nephritis in adult patients who are receiving standard therapy.,The safety and efficacy of BENLYSTA have not been evaluated in patients with severe active central nervous system lupus.