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USDailyMed:Vincristine AU:D L01CA02(WHO) AU:S4(Prescription only)CA:℞-onlyUK:POM(Prescription only)US:℞-only (3aR,3a1R,4R,5S,5aR,10bR)-Methyl 4-acetoxy-3a-ethyl-9-((5S,7S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-2,4,5,6,7,8,9,10-octahydro-1H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl)-6-formyl-5-hydroxy-8-methoxy-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate 57-22-7Y 5978 6785 DB00541Y 5758Y 5J49Q6B70F D08679Y CHEBI:28445Y ChEMBL303560N DTXSID1032278 Interactive image CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]7‍‍‍‍‍‍​​​‍​​​​​​8CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O InChI=1S/C46H56N4O10/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)NKey:OGWKCGZFUXNPDA-XQKSVPLYSA-NY Vincristine, also known asleurocristineand sold under the brand nameOncovinamong others, is achemotherapymedication used to treat a number of types ofcancer.This includesacute lymphocytic leukemia,acute myeloid leukemia,Hodgkin lymphoma,neuroblastoma, andsmall cell lung canceramong others.It is given intravenously. Most people experience some side effects from vincristine treatment.Commonly it causes a change in sensation, hair loss, constipation, difficulty walking, and headaches.Serious side effects may includeneuropathic pain, lung damage, orlow white blood cellswhich increases the risk of infection.Use duringpregnancymay result inbirth defects.It works bystopping cells from dividing properly.It is vital that it not be givenintrathecally, as this may kill. Vincristine was first isolated in 1961.It is on theWorld Health Organization's List of Essential Medicines.It is avinca alkaloidthat can be obtained from the Madagascar periwinkleCatharanthus roseus.