Pharmacotherapeutic group: Antiseptics and disinfectants
ATC code: D08AC52
Dexpanthenol, the active substance of Bepanthen Plus, is rapidly converted within skin cells to pantothenic acid (vitamin B5) and therefore exerts the same effect as the vitamin itself.
Pantothenic acid is a component of the essential coenzyme A (CoA). In the form of acetyl coenzyme A, CoA plays a central role in the metabolism of all cells. Pantothenic acid is indispensable to the body for the formation and regeneration of the skin and mucous membranes.
Chlorhexidine dihydrochloride is a well-known and well-tolerated antiseptic and bactericidal compound active against Gram-positive bacteria, with notable sensitivity against Staphylococcus aureus, which is implicated in many skin infections. Activity against Gram-negative pathogens is somewhat less pronounced.
Certain species of Pseudomonas and Proteus are wholly resistant. Chlorhexidine demonstrates negligible antimycotic activity and is ineffective against viruses.
⚠️ Warnings
Avoid contact with the eyes, ears, and mucous membranes.
Bepanthen Plus should not be used on skin injuries or irritations that do not present a risk of infection (for example, sunburn). In such cases, products containing dexpanthenol alone are recommended:
Bepanthen Cream, which is of an aqueous composition, easily spreadable and rapidly absorbed, and also suitable for the care of weeping wounds, hair-bearing areas, and the most exposed sites of the skin (such as the face, elbows, and hands).
Rare but serious allergic reactions or anaphylaxis may occur with the use of products containing chlorhexidine. If signs of a serious allergic reaction appear (breathing difficulties, wheezing, facial swelling, rapidly progressing urticaria, widespread rash, or shock), use of the product must be discontinued immediately and medical attention sought.
Bepanthen Plus contains cetyl alcohol, stearyl alcohol, and wool fat.
Cetyl alcohol, stearyl alcohol, and wool fat may cause local skin reactions (e.g. contact dermatitis).
PillsCard reference image