Estrogen

AU:B3 G03DB08(WHO)G03AB08(WHO)G03FA15(WHO) (combinations withestrogens) AU:S4(Prescription only) 2-[(8S,13S,14S,17R)-17-hydroxy-13-methyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]acetonitrile 65928-58-7Y[pubchem] 68861 7654 DB09123Y 62093Y 46M3EV8HHE D03799Y CHEBI:70708Y ChEMBL1201864Y DTXSID80891478 Interactive image C[C@]12CCC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]2(CC#N)O InChI=1S/C20H25NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-10H2,1H3/t17-,18+,19+,20-/m1/s1N[pubchem]Key:AZFLJNIPTRTECV-FUM‍‍‍‍‍‍​​​‍​​​​​​NGEBKSA-NN[pubchem] Dienogest, sold under the brand nameVisanne(manufactured byBayer AG) among others, is aprogestinmedication which is used inbirth control pillsand in the treatment ofendometriosis.It is also used inmenopausal hormone therapyand to treatheavy periods.Dienogest is available both alone and in combination withestrogens.It is takenby mouth. Side effectsof dienogest includemenstrual irregularities,headaches,nausea,breast tenderness,depression, andacne, among others.Dienogest is a progestin, or asyntheticprogestogen, and hence is anagonistof theprogesterone receptor, thebiological targetof progestogens likeprogesterone.It is a unique progestogen, with strong effects in theuterus.The medication has someantiandrogenicactivity, which may help to improveandrogen-dependentsymptomslikeacne, and has no other importanthormonalactivity. Dienogest was discovered in 1979 and was introduced for medical use in 1995.Additional formulations of dienogest were approved between 2007 and 2010.It is sometimes referred to as a "fourth-generation" progestin.Dienogest is marketed widely throughout the world.It is available as ageneric medication.