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Manufacturer
Nederlandse Service Apotheek Beheer B.V. (NL)
ATC Code
R06AX13
Source
CBG
USDailyMed:Loratadine
AU:B1
R06AX13(WHO)
AU:OTCCA:OTCUK:General sales list(GSL, OTC) / PharmacyUS:OTC/ Rx-only
Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate
79794-75-5Y
3957
7216
DB00455N
3820Y
7AJO3BO7QN
D00364Y
CHEBI:6538Y
ChEMBL998Y
DTXSID2023224
Interactive image
O=C(OCC)N4CC/C(=C2/c1ccc(Cl)cc1CCc3cccnc23)CC4
InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3YKey:JCCNYMKQOSZNPW-UHFFFAOYSA-NY
Loratadine, sold under the brand nameClaritinamong others, is a medication used to treatallergies.This includesallergic rhinitis(hay fever) andhives.It is also available in drug combinations such asloratadine/pseudoephedrine, in which it is combined withpseudoephedrine, anasal decongestant.It is taken orally.
Common side effects include sleepiness, dry mouth, and headache.Serious side effects are rare and includeallergic reactions,seizures, andliver problems.Use duringpregnancyappears to be safe but has not been well studied.It is not recommended in children less than two years old.It is in thesecond-generation antihistaminefamily of medications.
Loratadine was patented in 1980 and came to market in 1988.It is on theWorld Health Organization's List of Essential Medicines.Loratadine is available as ageneric medication.In the United States, it is availableover the counter.In 2023, it was the 105th most commonly prescribed medication in the United States, with more than 6million prescriptions;and the combination withpseudoephedrinewas the 300th most commonly prescribed medication in the United States, with more than 400,000 prescriptions.
⚠️ Warnings
• Caution should be exercised in patients with liver or kidney disease, and epilepsy.
• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
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Verified by medical editor
Dr. Ozarchuk, PharmD · April 2026
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Source: РЛС РФ · rlsnet.ru
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