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СОФАРМА АД (BG)
ATC Code
A02BA 2
Source
BDA
USDailyMed:Ranitidine
AU:B1
A02BA02(WHO)A02BA07(WHO) (ranitidine bismuth citrate)
AU:S4(Prescription only) / S2 (Pharmacy Medicine)CA:℞-only/ OTCUS:℞-only/ OTCEU:Rx-only
N-(2-[(5-[(Dimethylamino)methyl]furan-2-yl)methylthio]ethyl)-N'-methyl-2-nitroethene-1,1-diamine
66357-35-5HCl:66357-59-3
3001055HCl:3033332
1234
DB00863HCl:DBSALT000487
4863HCl:43590
884KT10YB7HCl:BK76465IHM
D00422HCl:D00673
CHEBI:8776HCl:CHEBI:8777
ChEMBL1790041HCl:ChEMBL2110372
DTXSID8045191
Interactive image
CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C
InChI=1S/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3Key:VMXUWOKSQNHOCA-UHFFFAOYSA-N
Ranitidine, sold under the brand nameZantacamong others, is amedicationused to decreasestomach acidproduction.It is used in the treatment ofpeptic ulcer disease,gastroesophageal reflux disease, andZollinger–Ellison syndrome.It can be given bymouth,injection into a muscle, orinjection into a vein.
In September 2019, the probablecarcinogenN-nitrosodimethylamine(NDMA) was discovered in ranitidine products from a number of manufacturers, resulting in recalls.In April 2020, ranitidine was withdrawn from the United States market and suspended in the European Union and Australia due to these concerns.A reformulated ranitidine was approved in Australia in October 2024,and in the United States in November 2025.
Common side effects includeheadaches, and pain or burning sensation if given by injection.Serious side effects may include cancer,liver problems, aslow heart rate,pneumonia, and the potential of maskingstomach cancer.It is also linked to an increased risk ofClostridioides difficilecolitis.Ranitidine is anH2histamine receptor antagonistthat works by blockinghistamine, thus decreasing the amount of acid released by cells of the stomach.
Ranitidine was discovered in England in 1976 and came into commercial use in 1981.It is on theWorld Health Organization's List of Essential Medicines.
⚠️ Warnings
• Caution should be exercised in patients with history of porphyria, kidney or liver disease; during pregnancy and breastfeeding.