Rimantadine

C(United States) J05AC02(WHO) US:℞-only 1-(adamantanyl)ethanamine 13392-28-4Y 5071 DB00478Y 4893Y 0T2EF4JQTU D08483Y ChEMBL959Y RIM (PDBe,RCSB PDB) DTXSID2023561 Interactive image NC(C)C13CC2CC(CC(C1)C2)C3 InChI=1S/C12H21N/c1-8(13)12-5-9-2-10(6-12)4-11(3-9)7-12/h8-11H,2-7,13H2,1H3YKey:UBCHPRBFMUDMNC-UHFFFAOYSA-NY Rimantadine(INN, sold under the trade nameFlumadine) is an orally administeredantiviral drugused to treat, and in rare cases prevent,influenzavirus Ainfection.‍​‍‍‍​‍‍‍‍‍‍‍‍​‍ When taken within one to two days of developing symptoms, rimantadine can shorten the duration and moderate the severity of influenza. Rimantadine can mitigate symptoms, including fever.Both rimantadine and the similar drugamantadineare derivates ofadamantane. Rimantadine is found to be more effective than amantadine because when used the patient displays fewer symptoms.Rimantadine was approved by theFood and Drug Administration(FDA) in 1994. Rimantadine was approved for medical use in 1993.Seasonal H3N2 and2009 pandemic flusamples tested have shown resistance to rimantadine, and it is no longer recommended to prescribe for treatment of the flu.