Alphagan Z Ophthalmic Solution

USDailyMed:Brimonidine AU:B3 D11AX21(WHO)S01EA05(WHO),S01EA55(WHO),S01GA07(WHO) AU:S4(Prescription only) /Schedule 2US:℞-only/ OTC 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl) quinoxalin-6-amine 59803-98-4Y 2435 520 DB00484Y 2341Y E6GNX3HHTE D07540Y CHEBI:3175Y ChEMBL844Y DTXSID3045221 Interactive image Brc2c1nccnc1ccc2N/C3=N/CCN3 InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)YKey:XYLJNLCSTIOKRM-UHFFFAOYSA-NY Brimonidineis anα2agonistme‍​‍‍‍​‍‍‍‍‍‍‍‍​‍dicationused to treatopen-angle glaucoma,ocular hypertension, androsacea.In rosacea it improves the redness.It is used aseye dropsor applied to the skin.It is also available in thefixed-dose combinationmedicationbrimonidine/timololalong withtimololmaleate. Common side effects when used in the eyes include itchiness, redness, and a dry mouth.Common side effects when used on the skin include redness, burning, and headaches.More significant side effects may includeallergic reactionsandlow blood pressure.Use inpregnancyappears to be safe.When applied to the eye it works by decreasing the amount ofaqueous humormade while increasing the amount that drains from the eye.When applied to the skin it works by causing blood vessels to contract. Brimonidine was patented in 1972 and came into medical use in 1996.It is available as ageneric medication.In 2023, it was the 213th most commonly prescribed medication in the United States, with more than 2million prescriptions.