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Manufacturer
ФАРМАКОНС АД (BG)
ATC Code
L02BG 3
Source
BDA
USDailyMed:Anastrozole
AU:C
L02BG03(WHO)
AU:S4(Prescription only)CA:℞-onlyUK:POM(Prescription only)US:℞-only
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
120511-73-1Y
2187
5137
DB01217Y
2102Y
2Z07MYW1AZ
D00960Y
CHEBI:2704Y
ChEMBL1399Y
DTXSID9022607
Interactive image
N#CC(C)(C)c1cc(Cn2cncn2)cc(c1)C(C)(C)C#N
InChI=1S/C17H19N5/c1-16(2,9-18)14-5-13(8-22-12-20-11-21-22)6-15(7-14)17(3,4)10-19/h5-7,11-12H,8H2,1-4H3YKey:YBBLVLTVTVSKRW-UHFFFAOYSA-NY
Anastrozole, sold under the brand nameArimidexamong others, is anantiestrogenicmedication used in addition to other treatments forbreast cancer.Specifically it is used forhormone receptor-positivebreast cancer.It has also been used to prevent breast cancer in those at high risk.It is takenorally.
Common side effects of anastrozole includehot flashes,altered mood,joint pain, andnausea.Severe side effects include an increased risk ofheart diseaseandosteoporosis.Use duringpregnancymay harm the fetus.Anastrozole is in thearomatase-inhibitingfamily of medications.It works by blocking theproductionofestrogensin the body, and hence hasantiestrogeniceffects.
Anastrozole was patented in 1987 and was approved for medical use in 1995.It is on theWorld Health Organization's List of Essential Medicines.Anastrozole is available as ageneric medication.In 2023, it was the 194th most commonly prescribed medication in the United States, with more than 2million prescriptions.
⚠️ Warnings
•Caution should be exercised in patients with history of moderate or severe liver impairment, excess fat, children.
Be sure to mention any of the following: medications that contain estrogen such as hormone replacement therapy (HRT) and hormonal contraceptives (birth control pills, patches, rings, and injections); raloxifene (Evista); and tamoxifen (Nolvadex) before starting therapy with Anastrozole.
• It may cause dizziness. Do not drive a car or operate machinery while driving this medication.
• Avoid alcohol consumption.
Do the lab test for menopause if status is doubtful.
Bone mass density (bone mineral density) test should be conducted at the start of the therapy and at regular intervals thereafter.
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Verified by medical editor
Dr. Ozarchuk, PharmD · April 2026
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Source: РЛС РФ · rlsnet.ru
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