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1000 j.m./0,5 ml, Roztwór do wstrzykiwań
INN: Epoetinum theta
Data updated: 2026-04-13
Available in:
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Form
Roztwór do wstrzykiwań
Dosage
1000 j.m./0,5 ml
Route
dożylna, podskórna
Storage
—
About This Product
User Reviews
Reviews reflect personal experiences and are not medical advice. Always consult your doctor.
Manufacturer
TEVA GmbH (Niemcy)
Composition
Epoetinum theta
ATC Code
B03XA01
Source
URPL
Biopoin contains epoetin theta, a recombinant human erythropoietin produced in Chinese hamster ovary cells, supplied as a sterile aqueous solution for subcutaneous or intravenous injection at 1000 IU/0.5 mL pre-filled syringe. Epoetin theta has the same 165-amino-acid sequence as endogenous human erythropoietin with a slightly modified glycosylation profile that gives it pharmacokinetic and stability properties distinct from epoetin alfa or beta. It binds the EPO receptor on bone-marrow erythroid progenitor cells (CFU-E and proerythroblasts), preventing their apoptosis and stimulating proliferation, differentiation, and maturation into mature erythrocytes — producing a dose-dependent rise in haemoglobin over 2-6 weeks. ATC class B03XA01 (other anti-anaemic preparations).
⚠️ Warnings
Target haemoglobin 10-12 g/dL; do not exceed 12 g/dL except in narrowly justified clinical settings. Optimise iron, vitamin B12, and folate status before and during therapy — most non-responders are functionally iron-deficient. Monitor blood pressure regularly. Investigate any abrupt loss of efficacy with rapidly falling haemoglobin and reticulocyte count by an anti-EPO antibody assay (suspected PRCA) and discontinue if confirmed. In oncology, use only when symptomatic anaemia limits quality of life and stop with chemotherapy completion. Different epoetins (alfa, beta, theta, zeta, darbepoetin) are not interchangeable; switching requires specialist supervision and dose re-titration.