NORMAL SERUM ALBUMIN (HUMAN)

( ARTG ) Normal Immunoglobulin-VF is indicated in the management of congenital and acquired forms of primary hypogammaglobulinaemia.‍‍‍‍‍‍​​​‍​​​​​​ It may also be of value in treating secondary forms of this disorder as in leukaemia, nephrosis and acute protein-losing enteropathy, particularly when there is a tendency to recurrent infection. In susceptible contacts of hepatitis A, measles and poliomyelitis, Normal Immunoglobulin-VF may be of value in preventing or modifying the disease. In general, the earlier in the incubation period of these diseases Normal Immunoglobulin-VF is given, the greater its effectiveness. Hepatitis A-Routine passive protection is recommended in persons exposed less than one week previously for the following categories of individuals, Household contacts of an index case, who have not already had hepatitis A or have no serological evidence of immunity to the virus. Common source exposures. When a vehicle such as food or water is identified as a common source of infection for multiple hepatitis cases, administration of Normal Immunoglobulin-VF should be considered for all those exposed to the source. Institutional contacts. Staff in institutions where hepatitis is endemic. Routine prophylaxis is not recommended for school, office, factory or hospital contacts. Rubella, Although Normal Immunoglobulin-VF can prevent or modify the clinical disease in susceptible rubella contacts if given within 72 hours of exposure, it does not prevent viraemia in such patients. It should, therefore, not be relied upon to prevent congenital malformations due to rubella if given to susceptible pregnant women during the first trimester. Measles (Morbilli), Normal Immunoglobulin-VF is indicated for protection against measles in persons exposed less than one week previously. It is recommended in children under six months of age whose mothers have not had the disease, in children between six months and three years of age who have not been actively immunised and in immunosuppressed contacts of the index case. Poliomyelitis, Normal Immunoglobulin-VF is recommended for susceptible contacts who have not been immunised against poliomyelitis.