What is Mekinist Film-Coated Tablets 0.5mg used for?

Trametinib belongs to a group of medicines called kinase inhibitors. It is prescribed for the treatment of a certain type of advanced stage skin cancer (melanoma) which has spread to other parts of the body or which cannot be treated by surgery. Trametinib is often given in combination with dabrafenib for patients with BRAF V600E or V600K mutations. It prevents the growth of cancer cells by blocking the MEK proteins which signals them to multiply.

What are the side effects of Mekinist Film-Coated Tablets 0.5mg?

General: Swelling of the face, arms, legs and feet, fever, weakness, diarrhea, pain in abdomen. Skin: Rashes, severe skin reactions, skin infections, nail disease, itching. Skin toxicity may be serious enough to require hospitalization. Cardiovascular system: High blood pressure, cardiomyopathy (heart muscle related diseases), heart failure. Central nervous system: Dizziness Respiratory: Shortness of breath, difficulty in breathing, lung diseases, pneumonitis, cough, nose bleed. Blood: Anemia, l

Does Mekinist Film-Coated Tablets 0.5mg interact with other medications?

Trametinib should be avoided with: CYP3A4 and CYP2C8 inducers or inhibitors when it is used along with dabrafenib.

Can Mekinist Film-Coated Tablets 0.5mg be used during pregnancy?

( AHT ) For the active ingredient trametinib You should seek advice from your doctor or pharmacist about taking this medicine. They can help you balance the risks and the benefits of this medicine during pregnancy.

What precautions should be taken with Mekinist Film-Coated Tablets 0.5mg?

•Do not use the drug if you are planning to become pregnant as trametinib may cause harm to the fetus. Monitor blood glucose levels while taking trametanib as the drug is capable of causing high blood sugar level. Blood pressure should be checked from time to time as tramatenib can cause hypertension. Trametanib may cause fertility problems. It should be avoided by women of child bearing age.

What ATC class does Mekinist Film-Coated Tablets 0.5mg belong to?

Mekinist Film-Coated Tablets 0.5mg: ATC G04BX13. ATC is the WHO Anatomical Therapeutic Chemical classification — it groups drugs by organ system and pharmacological mechanism.

OTC

Mekinist Film-Coated Tablets 0.5mg

膜衣錠

INN: Trametinib Dimethyl Sulfoxide

Data updated: 2026-04-11

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膜衣錠

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