Pharmacotherapeutic group: Drugs used in addictive disorders, drugs used in alcohol dependence, ATC code: N07BB03
Mechanism of action
Acamprosate (calcium acetylhomotaurinate) has a chemical structure like that of amino acid neuromediators, such as taurine or gamma-amino-butyric acid (GABA), including an acetylation to permit passage across the blood brain barrier.
Pharmacodynamic effects
Acamprosate may act by stimulating GABAergic inhibitory neurotransmission and antagonising excitatory amino-acids, particularly glutamate.
Animal experimental studies have demonstrated that acamprosate affects alcohol dependence in rats, decreasing the voluntary intake of alcohol without affecting food and total fluid intake.
⚠️ Warnings
No special requirements for disposal.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements.